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Table 10 Additional myocardial morphology comparison: acute myeloid leukemia (AML) vs solid tumors (STs)

From: Differential cardiac impacts of hematological malignancies and solid tumors: a histopathological and biomarker study

 

AML (n=47)

ST (n=36)

p Value

Cytoplasmic Vacuoles

  

0.067

0 (absent)

42 (89%)

36 (100%)

 

1 (mild)

5 (11%)

0 (0%)

 

2 (moderate/severe)

0 (0%)

0 (0%)

 

Nuclear Atypia

  

0.4

0 (absent)

11 (23%)

10 (29%)

 

1 (mild)

27 (57%)

22 (63%)

 

2 (moderate/severe)

9 (19%)

3 (8.6%)

 

Lipofuscin Deposition

  

0.4

0 (absent)

0 (0%)

0 (0%)

 

1 (mild/moderate)

29 (62%)

18 (50%)

 

2 (severe)

18 (38%)

18 (50%)

 

Myocyte apposition

  

0.13

0 (absent)

0 (0%)

0 (0%)

 

1 (mild/moderate)

39 (83%)

24 (67%)

 

2 (severe)

8 (17%)

12 (33%)

 
  1. The tissue samples that met the acceptable criteria for histologic analysis of specific features were limited, resulting in smaller sample sizes