Table 5 Comparison: acute myeloid leukemia (AML) vs solid tumors (STs)
|  | AML (n = 93)a | ST (n = 164)a | p Value |
|---|---|---|---|
Demographic parameters | |||
 Age (yrs) | 58 (14) | 62 (13) | 0.032 |
 Race |  |  | 0.60 |
 White | 74 (80%) | 120 (73%) |  |
 Black | 10 (11%) | 20 (12%) |  |
 Hispanic | 2 (2.2%) | 4 (2.4%) |  |
 Other Race | 7 (7.5%) | 20 (12%) |  |
 Female | 29 (31%) | 64 (39%) | 0.20 |
 Body mass index (kg/m2) | 31 (9) | 28 (8) | 0.027 |
 Tobacco use | 55 (63%) | 115 (74%) | 0.067 |
Cardiac biomarkers | |||
 Ejection fraction (%) | 62 (11) | 64 (12) | 0.60 |
 B-type natriuretic peptide (pg/ml) | 2,422 (4,770) | 867 (1,317) | 0.010 |
 Troponin I (ng/ml) | 0.9 (2.4) | 4.6 (17.2) | 0.055 |
 Creatine Kinase MB (ng/ml) | 5 (11) | 12 (29) | 0.067 |
 Hemoglobin (g/dl) | 6.73 (0.95) | 8.06 (1.97) |  < 0.001 |
Post-mortem parameters | |||
 Atherosclerosis (more than mild) | 31 (40%) | 74 (50%) | 0.20 |
 Heart weight (g) | 494 (110) | 440 (129) | 0.001 |
 Left ventricle thickness (cm) | 1.71 (0.39) | 1.63 (0.41) | 0.19 |
 Right ventricle thickness (cm) | 0.60 (0.25) | 0.52 (0.23) | 0.039 |
 Septal wall thickness (cm) | 1.52 (0.37) | 1.50 (0.39) | 0.82 |
Myocardial morphology | |||
 Collagen fiber alignment | 0.66 (0.33) | 0.83 (0.12) | 0.14 |
 Interstitial fibrosis (%) | 0.23 (0.09) | 0.22 (0.08) | 0.97 |
 Cardiomyocyte nuclei (#) | 52 (21) | 72 (23) | 0.002 |
 Cardiomyocyte minor axis length (µm) | 27 (4) | 25 (3) | 0.065 |