Table 4 Comparison of the changes in CMR characteristics of LV by randomization groups

LV EF

0.011

 Baseline

61.6 ± 4.4

60.9 ± 4.4

62.4 ± 5.3

61.5 ± 3.8

0.64

1 year

59.6 ± 5.4

56.5 ± 5.1

60.0 ± 5.9

61.5 ± 4.4^||

0.019

 Extended FU

58.8 ± 5.3

59.1 ± 4.9

58.4 ± 5.9

58.9 ± 5.2

0.94

 Change from baseline to extended FU

-2.8 ± 4.6^‡

-1.9 ± 4.1

-4.0 ± 4.6^‡

-2.6 ± 4.8^‡

0.42

 Change from 1 year to extended FU

-0.8 ± 5.3

2.6 ± 5.4

-1.6 ± 3.8

-2.6 ± 5.3^||

0.010

LV EDV

0.75

 Baseline

123.6 ± 25.1

130.3 ± 30.4

117.3 ± 20.9

123.7 ± 23.8

0.36

 12-month

137.7 ± 26.7

140.9 ± 24.7

135.1 ± 28.2

137.4 ± 27.8

0.84

 Extended FU

123.0 ± 25.1

124.8 ± 23.2

120.8 ± 28.2

123.4 ± 24.9

0.91

 Change from baseline to extended FU

-0.6 ± 18.2

-5.5 ± 26.6

3.6 ± 14.8

-0.3 ± 12.5

0.39

Change from 1 year to extended FU

-14.7 ± 19.0^§

-16.1 ± 18.6^§

-14.3 ± 22.0^§

-14.0 ± 17.6^§

0.94

LV ESV

0.061

 Baseline

47.4 ± 10.9

50.8 ± 12.8

44.2 ± 10.4

47.4 ± 9.6

0.25

 1 year

56.2 ± 14.5

61.8 ± 14.6

54.8 ± 15.3

53.2 ± 13.2

0.19

 Extended FU

50.9 ± 12.6

51.1 ± 11.0

50.9 ± 16.1

50.7 ± 11.1

0.999

 Change from baseline to extended FU

3.5 ± 9.0^‡

0.3 ± 10.2

6.8 ± 9.0^‡

3.3 ± 7.5

0.13

 Change from 1 year to extended FU

-5.3 ± 10.8^§

-10.7 ± 12.0^§

-3.8 ± 9.4

-2.5 ± 9.9

0.06

LV mass

0.85

 Baseline

91.6 ± 15.0

90.5 ± 16.1

92.3 ± 12.5

91.8 ± 16.4

0.95

 1 year

92.5 ± 14.5

93.2 ± 15.3

92.1 ± 14.4

92.2 ± 14.6

0.97

 Extended FU

65.7 ± 12.7

64.9 ± 14.3

67.0 ± 12.1

65.3 ± 12.4

0.89

 Change from baseline to extended FU

-25.9 ± 8.9^‡

-25.6 ± 8.9^‡

-25.3 ± 9.6^‡

-26.5 ± 8.8^‡

0.92

 Change from 1 year to extended FU

-26.7 ± 9.8^§

-28.3 ± 11.4^§

-25.1 ± 10.2^§

-26.9 ± 8.6^§

0.66